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Darui Wang, Hongmin Sun, Wei Liu, Zhenhao Shen, Weimin Yang
《化学科学与工程前沿(英文)》 2020年 第14卷 第2期 页码 248-257 doi: 10.1007/s11705-019-1853-9
关键词: hierarchical ZSM-5 zeolite protective desilication piperidine radial mesopores benzene alkylation
Enhancing thermostability of -mannanase by protective additives
LIU Zhaohui, QI Wei, WU Weina, LIU Yue, HE Zhimin
《化学科学与工程前沿(英文)》 2008年 第2卷 第4期 页码 439-442 doi: 10.1007/s11705-008-0062-8
关键词: protective additive g/L orthogonal experimental combination additive corresponding
The influence of brain death on donor liver and the potential mechanisms of protective intervention
null
《医学前沿(英文)》 2011年 第5卷 第1期 页码 8-14 doi: 10.1007/s11684-011-0109-y
Brain-dead donors have become one of the main sources of organs for transplantation in Western countries. The quality of donor organs is closely related to the outcome of the transplantation. Experimental studies have confirmed the inferior graft survival of livers from brain-dead donors compared with those from living donors. Studies conducted in the past 10 years have shown that brain death is associated with effects on the decreased donor organ quality. However, whether the decrease in the viability of donor organs is caused by brain death or by the events before and after brain death remains uncertain. The purpose of this review is to introduce the advances and controversies regarding the influence of brain death on the viability of donor livers and to summarize the mechanisms of the different protective interventions for donor livers.
关键词: brain death donor liver
Yuehua Fang, Fan Yang, Xuan He, Xuedong Zhu
《化学科学与工程前沿(英文)》 2019年 第13卷 第3期 页码 543-553 doi: 10.1007/s11705-018-1778-8
关键词: steam treatment alkaline treatment hierarchical ZSM-5 methanol aromatization
PAK1 is a novel cardiac protective signaling molecule
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 399-403 doi: 10.1007/s11684-014-0380-9
We review here the novel cardiac protective effects of the multifunctional enzyme, p21-activated kinase 1 (PAK1), a member of a serine/threonine protein kinase family. Despite the large body of evidence from studies in noncardiac tissue indicating that PAK1 activity is key in the regulation of a number of cellular functions, the role of PAK1 in the heart has only been revealed over the past few years. In this review, we assemble an overview of the recent findings on PAK1 signaling in the heart, particularly its cardiac protective effects. We present a model for PAK1 signaling that provides a mechanism for specifically affecting cardiac cellular processes in which regulation of protein phosphorylation states by protein phosphatase 2A (PP2A) predominates. We discuss the anti-adrenergic and antihypertrophic cardiac protective effects of PAK1, as well as its role in maintaining ventricular Ca2+ homeostasis and electrophysiological stability under physiological, β-adrenergic and hypertrophic stress conditions.
Antioxidative potential of metformin: Possible protective mechanism against generating OH radicals
Huibin Guo, Ning Wang, Xiang Li
《环境科学与工程前沿(英文)》 2021年 第15卷 第2期 doi: 10.1007/s11783-020-1313-2
关键词: Antioxidative potential Metformin Mechanism OH radical Health protection.
《化学科学与工程前沿(英文)》 2023年 第17卷 第10期 页码 1544-1554 doi: 10.1007/s11705-022-2288-2
关键词: cellulose-based nanocomposite biodegradable antibacterial fabric nano-copper ions face masks
Effect of hyperlipidemia on endothelial VCAM-1 expression and the protective role of fenofibrate
WU Jun, LIN Jinchao, HE Zhaochu, OU Biru, GUO Haisen
《医学前沿(英文)》 2007年 第1卷 第4期 页码 356-358 doi: 10.1007/s11684-007-0068-5
关键词: endothelial 16-week treatment leukocyte accumulation mg/kg NO
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 490-498 doi: 10.1007/s11684-016-0470-y
This study evaluated the immunogenicity and protective immunity of a Hemophilus influenzae b (Hib) polysaccharide conjugate vaccine with the pneumococcal surface adhesin A (PsaA) protein carrier in young mice. The Hib polysaccharide was conjugated with the rPsaA protein carrier, which was produced using recombinant DNA technology. A total of 15 young mice aged 3 weeks to 5 weeks were immunized with the conjugate vaccine, and another 15 young mice of the same age were immunized with the licensed Hib-tetanus toxoid (TT) vaccine. Furthermore, the third group of 15 young mice was inoculated with phosphate buffer saline as control. The immunized mice were inoculated with pneumococcus in the middle ear. Results showed that IgG antibody responses against both the PsaA protein and Hib polysaccharide were observed in the Hib-PsaA group. However, no statistical difference was observed in the titer of IgG against the Hib polysaccharide between Hib-PsaA and Hib-TT groups. The elimination rate of pneumococcus and the inflammation of the middle ear showed the effectiveness of protective immunity against otitis media caused by pneumococcus. Our results suggest that the Hib polysaccharide can be successfully conjugated with rPsaA via amide condensation. This new Hib-PsaA conjugate vaccine can induce both anti-PsaA and anti-Hib immune responses in young mice and elicit effective protection against acute otitis media caused by pneumococcus.
关键词: conjugate vaccine pneumococcal surface adhesin A Hemophilus influenzae b immunogenicity otitis media
PROTECTIVE ROLES OF D1 PROTEIN TURNOVER AND THE XANTHOPHYLL CYCLE IN TOMATO (
Tao LU, Jiazhi LU, Mingfang QI, Zhouping SUN, Yufeng LIU, Tianlai LI
《农业科学与工程前沿(英文)》 页码 262-279 doi: 10.15302/J-FASE-2021383
关键词: D1 turnover photoinhibition photoprotection photosynthesis tomato xanthophyll cycle
Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats
null
《医学前沿(英文)》 2015年 第9卷 第3期 页码 368-373 doi: 10.1007/s11684-015-0403-1
Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental ischemia/reperfusion (I/R) injury in pulmonary, intestinal, and myocardial tissue. However, its protective abilities against I/R injury in the liver are unknown. We investigated the potential role of GLP-2 pretreatment on hepatic I/R injury in rats. A total of 24 rats were randomly divided into three groups (n = 8). The first group was the control group; the second group was the vehicle-treated hepatic ischemia/reperfusion (HIR, vehicle saline-treated) group; and the third group was the GLP-2 pretreated I/R (GLP2-IR) group. Each rat in the third group was intraperitoneally administered 5 μg GLP-2 for 5 d before the procedure. A portal triad was created to induce ischemia with a vascular atraumatic clamp. After 40 min, the clamp was released to initiate hepatic reperfusion for 6 h. Blood samples and tissue specimens from the liver were obtained. Alanine aminotransferase, aspartate aminotransferase, and total bilirubin levels significantly increased in the saline-treated HIR group (P<0.001), whereas GLP-2 pretreatment significantly decreased their levels (P<0.01). Our data suggested that GLP-2 pretreatment may have a protective effect on liver I/R injury. However, dose-response studies are necessary to determine the most effective dose.
关键词: ischemia/reperfusion liver glucagon-like peptide-2 alanine aminotransferase
范鹏贤,钱七虎,王明洋
《中国工程科学》 2013年 第15卷 第5期 页码 47-58
防护工程是国防威慑力量的重要组成部分,具有重要的战略地位。美俄等军事大国大力发展的深钻地(核)武器已经对我国重要防护工程的生存造成了严重的威胁。本文总结了外军现役钻地(核)武器的性能指标与发展前景,对钻地武器的毁伤效应进行了评估和分析,综述了侵彻效应、爆炸成坑效应、爆炸地冲击效应等方面的研究成果。针对新时期的主要威胁,简述了提高防护工程防护能力的主要措施和技术途径,提出了主被动结合的综合防护体系、深部非线性岩体力学、摆型波与超低摩擦现象、多弹聚集打击效应等目前亟需开展研究的关键科学问题。
缪小平,彭福胜,耿世彬,范良凯,江 丰
《中国工程科学》 2013年 第15卷 第5期 页码 84-94
本文指出我国设备自动化系统存在的主要问题是将系统的集成作为弱电集成,导致自动化系统和设备系统相脱节。分析了设备自动化系统集成的目标、阶段划分及其评价标准。提出防护工程自动化系统与设备系统一体化集成的方法:瞄准设备自动化系统预期目标,在设计、施工、编程调试各个环节,甚至产品开发阶段,必须密切加强自动化系统与设备系统配合。
袁 辉,王凤山,许继恒,付成群
《中国工程科学》 2013年 第15卷 第5期 页码 106-112
为有效表示坑道工程空间对象,并有效支持动荷段实体的各种拓扑操作和毁伤分析等军事应用,提出了坑道工程动荷段实体模型构件化设计解决方案和设计质量的直觉模糊判决方法。适应坑道工程动荷段实体模型构件化设计的多样性特征和有效性验证约束,确定直觉模糊的正负理想构件化设计事件,比较构件化设计事件与正负理想事件的距离,建立坑道工程动荷段实体模型构件化设计事件的优势度计算模型,进而得到构件化设计事件集合的序列。案例表明,方法有效解决了坑道工程动荷段实体模型构件化设计质量判决问题,为科学的坑道工程动荷段实体模型设计实践提供了一种理论和方法。
Protective roles of heat stress on the neurons in hippocampal CA1 region of mice
WANG Chunxu, WANG Hanxing
《医学前沿(英文)》 2007年 第1卷 第4期 页码 418-422 doi: 10.1007/s11684-007-0082-7
标题 作者 时间 类型 操作
Hierarchical ZSM-5 zeolite with radial mesopores: Preparation, formation mechanism and application for benzene alkylation
Darui Wang, Hongmin Sun, Wei Liu, Zhenhao Shen, Weimin Yang
期刊论文
Enhancing thermostability of -mannanase by protective additives
LIU Zhaohui, QI Wei, WU Weina, LIU Yue, HE Zhimin
期刊论文
The influence of brain death on donor liver and the potential mechanisms of protective intervention
null
期刊论文
Dealumination and desilication for Al-rich HZSM-5 zeolite via steam-alkaline treatment and its application
Yuehua Fang, Fan Yang, Xuan He, Xuedong Zhu
期刊论文
Antioxidative potential of metformin: Possible protective mechanism against generating OH radicals
Huibin Guo, Ning Wang, Xiang Li
期刊论文
Nano-copper ions assembled cellulose-based composite with antibacterial activity for biodegradable personal protective
期刊论文
Effect of hyperlipidemia on endothelial VCAM-1 expression and the protective role of fenofibrate
WU Jun, LIN Jinchao, HE Zhaochu, OU Biru, GUO Haisen
期刊论文
Immunogenicity and protective immunity against otitis media caused by pneumococcus in mice of Hib conjugate
null
期刊论文
PROTECTIVE ROLES OF D1 PROTEIN TURNOVER AND THE XANTHOPHYLL CYCLE IN TOMATO (
Tao LU, Jiazhi LU, Mingfang QI, Zhouping SUN, Yufeng LIU, Tianlai LI
期刊论文
Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats
null
期刊论文